Authors: Sewar Al-Jarrah, and Bayan Ali Alyousef
DOI:
JORDANIAN JOURNAL OF ENGINEERING AND CHEMICAL INDUSTRIES (JJECI)
Pages: 85-101
Abstract
Magnetic nanoparticles (MNPs) are of great interest due to their intriguing properties and their vast applicability, notably in biomedicine. Their synthesis, functionalization, and utilization are addressed herein under review with specific focus being put on drug delivery using iron oxide nanoparticles (IONPs), magnetic resonance imaging (MRI), hyperthermia, and bio-sensing. A systematic literature review approach was used, comparing studies from 2010 to 2023 to include both established knowledge and new trends. Different synthesis routes, such as co-precipitation, sol-gel synthesis, and thermal decomposition, and surface functionalization strategies are presented to increase stability and biocompatibility. Although they hold great promise, toxicity, regulatory, and scalability issues limit clinical translation. Overcoming these shortcomings using cutting-edge biocompatible coatings, enhanced large-scale production methods, and regulated standardization of legislative mechanisms will be essential for the long-term commercialization of MNPs. This review offers a glimpse into current advancements and forthcoming future directions in research needed to realize the complete potential of MNPs in biomedical and industrial applications.
Paper type: Research Paper
Keywords:. Biomedical Applications, IONPs, In-Vivo, In-Vitro, Toxicity
Citation: Al-Jarrah, S., and Bayan, A. Nanotechnology and Applications of Magnetic Nanoparticles, A Review”, Jordanian Journal of Engineering and Chemical Industries,
Vol. 8, No.1, pp: 85-101 (2025).
